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FDA Approves Cambia™ For Migraine
Kowa Pharmaceuticals America, Inc. (KPA), a privately-held specialty pharmaceutical company headquartered in Montgomery, AL, announced today that the U.S. Food and Drug Administration (FDA) has approved Cambia™, a diclofenac-based non-steroidal anti-inflammatory drug ("NSAID") combined with potassium bicarbonate, for the treatment of acute migraine with or without aura in adults.
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Senate Dems Seek Compromise On Contentious Health Reform Issues
A leading Democratic senator, Kent Conrad, D-N.D., said Sunday Democrats would need Republican support to make ambitious proposals to overhaul the health system a reality, the Associated Press reports. "Look, there are not the votes for Democrats to do this just on our side of the aisle," said Conrad, who chairs the Budget Committee. Democrats remain divided over the plans, prompting the Republican leader, Sen. Mitch McConnell, R-Ky., to say, "The only thing bipartisan about the measure so far is the opposition to it" (7/26).
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Advocacy Group, N.D. Abortion Clinic File Lawsuit To Block State Ultrasound Law
The Red River Women"s Clinic in Fargo, N.D., went to court on Thursday to block a state law from going into effect that would require the clinic to give women the option to view ultrasound images and hear a fetal heartbeat 24 hours before receiving abortion services, the AP/Bismarck Tribune reports. The suit was filed in East Central District Court by the Center for Reproductive Rights on behalf of the clinic, which is the only abortion clinic in North Dakota. In the lawsuit, the clinic asked the court to issue a temporary injunction to prevent the law from taking effect on Aug. 1. A hearing has been scheduled for July 30.Suzanne Stolz, an attorney for CRR, said the law is "unconstitutional"” because it "creates an undue burden on a woman"s right to have an abortion." In a statement, CRR said that the law requires an audible fetal heartbeat consistent with "standard medical practice in the community." However, the Center said no such standard exists. In addition, Stolz said that the North Dakota law is less clear than laws in other states with ultrasound mandates that include a fetal heartbeat provision, including Georgia, Indiana, Kansas, Mississippi, Oklahoma and Wisconsin. Furthermore, CRR said that the equipment needed to provide the audible heartbeat would be expensive for the clinic, although it did not say what the cost would be.Tammi Kromenaker, director of the clinic, said it has offered women the option of viewing an ultrasound image since 2008. She said that the issue with the law is that it is not clear about whether a woman who chooses to view the image must also listen to the fetal heartbeat -- which sometimes cannot be heard in the early stages of pregnancy -- and about the level of technology the clinic must provide.Mary Spaulding Balch, a spokesperson for the National Right to Life Committee, said that the law is not burdensome to women seeking abortions and that it would only require the clinic to use "a simple device used by obstetrician[s] that amplifies" a fetal heartbeat. State Rep. Bette Grande (R), a sponsor of the law, said that the law does not require the Red River clinic to perform the ultrasound. She added that a woman seeking an abortion could receive the image and audio from another clinic prior to the procedure. Grande also noted that the law does not require women to view the ultrasound image and hear the fetal heartbeat -- it "just says they will have this opportunity" (MacPherson, AP/Bismarck Tribune, 7/24).
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Transatlantic Co-Operation Leads To Major Scientific CMOS (sCMOS) Technology Breakthrough

CMOS image sensor (CIS) technology stands on the brink of fulfilling its potential to become the global detector platform of choice for scientific photonics applications that require world class performance in the fields of sensitivity, speed, dynamic range, resolution, and field of view. The results of pioneering work, pooled res and shared expertise by scientists from Andor Technology (Northern Ireland), Fairchild Imaging (United States) and PCO (Germany) were revealed yesterday with the publication of a ground-breaking white paper at the Laser Conference and Exhibition in Munich (15 - 18 June 2009). The document presents sCMOS, a breakthrough technology based on next-generation CIS design and fabrication techniques. sCMOS is poised for widespread recognition as a true scientific grade CIS, capable of out-performing most scientific imaging devices on the market today. Unlike previous generations of CMOS and CCD-based sensors, sCMOS is uniquely capable of simultaneously offering: extremely low noise, rapid frame rates, wide dynamic range, high quantum efficiency (QE), high resolution, and a large field of view. "This announcement is a great moment for all three companies, who have come together in a true spirit of commitment to reach a shared goal," said Fairchild Imaging"s Colin Earle. "We have reached a "leap forward" point, where we can confidently claim that the next significant wave of advancement in high-performance scientific imaging capability has come from the CIS technology stable" added Dr. Colin Coates, Andor Technology. Dr. Gerhard Holst, PCO, said "Scientific CMOS (sCMOS) technology stands to gain widespread recognition across a broad gamut of demanding imaging applications, carrying an advanced set of performance features that renders it entirely suitable to high fidelity, quantitative scientific measurement." Current scientific imaging technology standards suffer limitations in relation to a strong element of "mutual exclusivity" between performance parameters, i.e. one can be optimized at the expense of others. sCMOS can be considered unique in its ability to concurrently deliver on many key parameters, whilst eradicating the performance drawbacks that have traditionally been associated with conventional CMOS imagers. Performance highlights of the first sCMOS technology sensor include: - Sensor format: 5.5 megapixels (2560(h) x 2160(v)) - Read noise: 16,000:1 (@ 30 frames/s) - QEmax.: 60% - Read out modes: Rolling and Global shutter (user selectable) Key applications for this new technology, already identified by Andor Technology, Fairchild Imaging and PCO include: - Live cell microscopy - Particle Imaging Velocimetry (PIV) - Single Molecule Detection - Super resolution microscopy - Lucky astronomy/imaging - Adaptive optics - Solar astronomy - Luminescence - Fluorescence Spectroscopy - Bio- and Chemo-Luminescence - Genome sequencing (2nd and 3rd generation) - High content screening - Biochip reading - Photovoltaic inspection - X-ray tomography - Machine vision - TV/Broadcasting - Spectral (hyperspectral) imaging - TIRF - Spinning disk confocal microscopy - FRET - FRAP - Laser Induced Breakdown spectroscopy Andor Technology


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