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Somnia Anesthesia: 3rd Study Confirms Anesthesia Improves Cancer Detection In Colonoscopies
More pre-cancerous polyps were found in colonoscopies performed with deep sedation primarily using Propofol than with milder sedation in which patients remained conscious, according to a recent study conducted by Katherine Hoda, M.D. of Oregon Health and Science University. This improvement in cancer detection will save lives and reduce the number of patients requiring surgery and chemotherapy.
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Insights Into Failed HIV-1 Vaccine Trial: Study
Following the disbandment of the STEP trial to test the efficacy of the Merck HIV-1 vaccine candidate in 2007, the leading explanation for why the vaccine was ineffective - and may have even increased susceptibility to acquiring the virus - centered on the hypothesis that high levels of baseline Ad5-specific neutralizing antibodies may have increased HIV-1 acquisition among the study subjects who received the vaccine by increasing Ad5-specific CD4+ T-cells that were susceptible to HIV-1 infection.
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The Right Cardiovascular Care For The Right Patient At The Right Time: ACC Positions Quality At Center Of Health-Care Reform
The American College of Cardiology (ACC) - long at the forefront of quality initiatives - is taking a leading role in health care reform. In partnership with patients, lawmakers and payers, the ACC is setting a new standard for health care delivery, one that centers on increasing the quality of care and ensuring greater patient access and value.
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International Workshop: Infant Formula Adulteration With Melamine Underscores Need For Better Detection Methods

Following the recent adulteration of infant formula and other milk products with the industrial chemical melamine, the U. S. Pharmacopeial (USP) Convention is holding an international workshop this week to explore better ways to detect deliberately falsified protein content in food ingredients. The presence of false protein can lead to illness and death, as with thousands of Chinese children in the tragic melamine adulteration of infant formula this year and with pets in the United States in 2007. Vulnerabilities in global supply chains for food and drug ingredients allow such adulteration to affect people worldwide, which is what happened in similar instances where toxic diethylene glycol was substituted for the sweetener glycerin in toothpaste and cough syrup. USP is a scientific nonprofit organization that sets official standards for the identity, quality, purity, and strength of prescription and over-the-counter drugs. USP also sets widely recognized standards for the quality and purity of food ingredients and dietary supplements. "This Food Protein workshop comes at a timely moment, as Congress considers legislation to better protect the U.S. food supply," said James Griffiths, Ph.D., USP"s vice president of food, dietary supplement and excipient standards. "Adhering to good manufacturing practices and utilizing third-party verification programs are important components of food safety efforts, but the international array of experts we"ve convened here agrees that testing to good quality standards is equally essential. The financial motivation for faking protein content can, unfortunately, be compelling. Rigorously defined quality standards and test methods can give manufacturers and regulators powerful tools to catch and discourage bad actors - helping to restore a shaken public confidence." Some have separated considerations of "quality" from those of "safety." However, at a time when public health is threatened by recurring incidents of deliberate or inadvertent food contamination, it is less plausible to do so - and consumers see little distinction between the two. Both quality and safety need to be addressed not only in terms of microbial contamination (such as Salmonella or E. coli), but in terms of the standards for ingredients used to make or fortify foods for human and animal consumption. USP publishes the Food Chemicals Codex (FCC), a collection of written quality standards that are used worldwide. USP also provides accompanying physical reference standards that food ingredients manufacturers can use to test the identity and quality of their products. As an organization that has been setting quality standards for pharmaceuticals for nearly 200 years, USP is well qualified to do so for food ingredients and dietary supplements. For more information on the Food Protein workshop, go to http://www.usp.org/meetings/workshops/foodProteinWorkshop2009.html. USP - Advancing Public Health Since 1820 The United States Pharmacopeial (USP) Convention is a scientific, nonprofit, standards-setting organization that advances public health through public standards and related programs that help ensure the quality, safety, and benefit of medicines and foods. USP"s standards are recognized and used worldwide. For more information about USP visit http://www.usp.org. Francine Pierson US Pharmacopeia


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