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To Flu Experts, 'Pandemic' Confirms The Obvious
"It came as no surprise on Thursday when the World Health Organization declared that the swine flu outbreak had become a pandemic," The New York Times reports. Swine flue has "reached 74 countries, and probably met the technical definition of a pandemic -- or global spread - weeks ago." Raising the alert from Phase 5 to Phase 6, the highest possible level, "does not mean that the illness, which has been mild in most people, has become any worse," because "the term pandemic reflects only the geographic spread of a new disease, not its severity." But it does "signal to countries to step up their efforts to deal with the disease," and it "also means that the health organization is asking drug makers to start making vaccine as quickly as possible." Dr. Margaret Chan, Director-General of the WHO, said while the disease has been mild so far, it "could change at any time and become more severe." It may also prove more deadly "when it reaches poor countries with higher rates of malnutrition, AIDS and other diseases that can lower people"s resistance to infection. Dr. Chan said rich countries should help poor ones less able to protect themselves" (McNeil and Grady, 6/11).
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Small Molecules Mimic Natural Gene Regulators
In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result when genes fail to turn on and off as they should.
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Evaluating More Lymph Nodes May Not Improve Identification Of Late-Stage Colorectal Cancer
Surgically removing and evaluating an increasing number of lymph nodes does not appear to identify a greater number of patients with stage III colorectal cancer, according to a report in the July issue of Archives of Surgery, one of the JAMA/Archives journals.
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Comment On The Study 'Filaggrin Gene Defects And Risk Of Developing Allergic Sensitisation And Allergic Disorders: Systematic Review And Meta-analysis

Dr Elaine Vickers, Research Relations Manager at Asthma UK, says: "This is an important piece of research which helps to explain why the majority of children with severe eczema go on to develop asthma in later childhood, as a result of their genetic make-up. "It may help us to understand why more than a million children in the UK are affected by asthma and identify those children who are at an increased risk of developing the condition after having eczema when they were younger. "This could be a significant step forward in helping to improve the diagnosis and treatment of children with allergy-related conditions, and reducing the numbers affected." Asthma UK


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