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Analysis Of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen In Once-Daily Dosing
A sub-analysis of a Phase IIb multinational study(1) with edoxaban(2) - an investigational oral Factor Xa inhibitor - provides insights into why patients with non-valvular atrial fibrillation (AF) receiving edoxaban once daily (QD) experienced fewer bleeding events than patients given edoxaban twice a day (BID). The analysis finds that bleeding associated with edoxaban is most closely correlated with minimum concentration levels of the drug in the blood, and that these trough levels may best predict bleeding events, rather than total exposure or maximum concentration levels.
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Lap-Band Weight-Loss Surgery Can Reverse Metabolic Syndrome In Obese Teens
A new study of obese adolescents has shown that laparoscopic gastric banding surgery -- the "Lap-Band" procedure -- not only helps them achieve significant weight loss but can also improve and even reverse metabolic syndrome, reducing their risk for cardiovascular disease and diabetes.
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Recovery Act Funding Supports 23 Fellowships For Early Career Scientists
Funding from the American Recovery and Reinvestment Act will allow the National Institutes of Health to create jobs for early career scientists and increase the ranks of researchers and clinicians working in the global health field. With $3 million in funding over the next 18 months, the NIH"s Fogarty International Center will be able to support 23 additional participants in its Clinical Research Training Scholars and Fellows Program.
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Association For Psychological Science Annual Convention

Program Highlights: APS President Walter Mischel will lead this year"s Presidential Symposium, "The New Genetics and What it Means for Psychological Science" on Saturday May 23 at 6:00 PM. Research on self-control has come a long way since Walter Mischel"s pivotal Marshmallow Task experiment in the late 1960s. Now, Mischel and colleagues are using fMRIs and genetic testing in hopes of outlining the neural circuitry of self-control. Michel"s newest endeavor will put decades of research to the test as he plans to see if self-control skills can be taught to schoolchildren and maintained over a long period of time. Richard Nisbett is presenting this year"s Bring the Family Address on Sunday, May 24 at 6:00PM. Nisbett"s research on the environment"s impact on intelligence reveals all geniuses aren"t born smart. Author Malcolm Gladwell called Nisbett"s new book, Intelligence and How to Get It: Why Schools and Cultures Count, "persuasive" and said "Few Americans have done as much [as Nisbett] to deepen our understanding of what it means to be human." As Nisbett"s research examines the environment"s impact on intelligence, Michael Meaney"s recent research findings reveal how our childhood environment affects the very expression of our genes. In particular, Meaney"s research showed how early childhood abuse can influence the development of a receptor linked to how we handle stress. Meaney is speaking during the Presidential Symposium "The New Genetics and What It Means for Psychological Science" on Saturday, May 23 at 6:00PM. Other Headliners Include: Martha Farah, University of Pennsylvania Award Address: "Cognitive Neuroscience in the 21st Century: From Lab and Clinic to Home, School, and Office" Elke Weber, Columbia University: Invited Address Symposium Presentation: "Multiple Determinants of Risk Taking" Sara M. Gorchoff, University of California, Berkeley: Invited Address Symposium Presentation: "Improvements in Marriage: Effects of Empty-Nest and Investment in a Satisfying Marriage" Michael Inzlicht, University of Toronto, Canada: Invited Address Symposium Presentation: "Belief in God Predicts Lower Anterior Cingulate Cortex Activity" Catherine Allen-West Association for Psychological Science


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